USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P30740 USC-OGP 2-DE database:  P30740 P30740 General information about the entry View entry in simple text format Entry name ILEU_HUMAN Primary accession number P30740 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Leukocyte elastase inhibitor; Short=LEI; AltName: Full=Monocyte/neutrophil elastase inhibitor; Short=EI; Short=M/NEI; AltName: Full=Peptidase inhibitor 2; Short=PI-2; AltName: Full=Serpin B1;. Gene name Name=SERPINB1 Synonyms=ELANH2, MNEI, PI2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0406: pI=5.66; Mw=43166 SPOT OGP-0409: pI=5.72; Mw=42642 SPOT OGP-0411: pI=5.82; Mw=42538 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0702: pI=5.83; Mw=44200 SPOT OGP-0706: pI=5.68; Mw=43115 SPOT OGP-0710: pI=5.79; Mw=42372 PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0944: pI=5.65; Mw=42003 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1185: pI=6.07; Mw=43048 Cross-references UniProtKB/Swiss-Prot P30740; ILEU_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ILEU_HUMAN Primary accession number P30740 Secondary accession number(s) A8K5L2 B4DNT0 Q53FB9 Q5W0E1 Q9UDF8 Sequence was last modified on  April 1, 1993 (version 1) Annotations were last modified on  March 15, 2017 (version 166) Name and origin of the protein Description RecName: Full=Leukocyte elastase inhibitor; Short=LEI; AltName: Full=Monocyte/neutrophil elastase inhibitor; Short=EI; Short=M/NEI; AltName: Full=Peptidase inhibitor 2; Short=PI-2; AltName: Full=Serpin B1; Gene name Name=SERPINB1 Synonyms=ELANH2, MNEI, PI2 Encoded on Name=SERPINB1; Synonyms=ELANH2, MNEI, PI2 Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Polymorphism; Protease inhibitor; Reference proteome; Serine protease inhibitor. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M93056; -; NOT_ANNOTATED_CDS; mRNA EMBL AF053630; AAC31394.1; -; Genomic_DNA EMBL AK291327; BAF84016.1; -; mRNA EMBL AK298044; BAG60342.1; -; mRNA EMBL BT006928; AAP35574.1; -; mRNA EMBL AK223370; BAD97090.1; ALT_INIT; mRNA EMBL AL139092; CAH73667.1; -; Genomic_DNA EMBL BC009015; AAH09015.1; -; mRNA CCDS CCDS4477.1; -. [P30740-1]; . PIR S27383; S27383; . RefSeq NP_109591.1; NM_030666.3. [P30740-1]; . RefSeq XP_011512635.1; XM_011514333.1. [P30740-1]; . RefSeq XP_011512636.1; XM_011514334.2. [P30740-1]; . UniGene Hs.381167; -; . PDB 4GA7; X-ray; 2.90 A; A/B=1-379 PDBsum 4GA7; -; . ProteinModelPortal P30740; -; . SMR P30740; -; . BioGrid 108307; 20; . IntAct P30740; 2; . MINT MINT-4999893; -; . STRING 9606.ENSP00000370115; -; . MEROPS I04.006; -; . iPTMnet P30740; -; . PhosphoSitePlus P30740; -; . DMDM 266344; -; . OGP P30740; -; . REPRODUCTION-2DPAGE IPI00027444; -; . EPD P30740; -; . PaxDb P30740; -; . PeptideAtlas P30740; -; . PRIDE P30740; -; . DNASU 1992; -; . Ensembl ENST00000380739; ENSP00000370115; ENSG00000021355. [P30740-1]; . GeneID 1992; -; . KEGG hsa:1992; -; . CTD 1992; -; . DisGeNET 1992; -; . GeneCards SERPINB1; -; . HGNC HGNC:3311; SERPINB1; . HPA HPA018871; -; . HPA HPA052642; -; . MIM 130135; gene; . neXtProt NX_P30740; -; . OpenTargets ENSG00000021355; -; . PharmGKB PA35046; -; . eggNOG KOG2392; Eukaryota; . eggNOG COG4826; LUCA; . GeneTree ENSGT00760000118789; -; . HOGENOM HOG000238519; -; . HOVERGEN HBG005957; -; . InParanoid P30740; -; . KO K13963; -; . OMA DRKTVKM; -; . OrthoDB EOG091G0ION; -; . PhylomeDB P30740; -; . TreeFam TF352619; -; . Reactome R-HSA-6798695; Neutrophil degranulation; . ChiTaRS SERPINB1; human; . GeneWiki SERPINB1; -; . GenomeRNAi 1992; -; . PMAP-CutDB P30740; -; . PRO PR:P30740; -; . Proteomes UP000005640; Chromosome 6; . Bgee ENSG00000021355; -; . CleanEx HS_SERPINB1; -; . ExpressionAtlas P30740; baseline and differential; . Genevisible P30740; HS; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005615; C:extracellular space; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:0004867; F:serine-type endopeptidase inhibitor activity; NAS:UniProtKB; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . InterPro IPR015557; Serpin_B1; . InterPro IPR023795; Serpin_CS; . InterPro IPR023796; Serpin_dom; . InterPro IPR000215; Serpin_fam; . PANTHER PTHR11461; PTHR11461; 1; . PANTHER PTHR11461:SF263; PTHR11461:SF263; 1; . Pfam PF00079; Serpin; 1; . SMART SM00093; SERPIN; 1; . SUPFAM SSF56574; SSF56574; 1; . PROSITE PS00284; SERPIN; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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